Using Machine Learning to Forecast the Progression of Alzheimer's Disease Lead Investigator: Jack Albright Institution : The Nueva School E-Mail : jacalbr@nuevaschool.org Proposal ID : 1183 Proposal Description: Due to the high failure rate among AD drug trials, AD research would benefit from the ability to use patients' biomarkers to predict their mental state in future years, as it would identify patients who are good candidates for clinical trials before they become symptomatic. Using another source of AD patient data, I developed a neural network model that was effective at predicting the progression of AD on a month-by-month basis, both in patients who were initially cognitively normal and in patients suffering from mild cognitive impairment. I plan to use the NACC data set to further develop this model as a predictive tool.